By David C. Anderson and Jeremy S. D. Winter (Eds.)
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Extra resources for Adrenal Cortex
Journal of Clinical Investigation, 6 7 , 1177-1182 SCHMIDTKE, J . , WIENKER, T . , FLÜGEL, M. a n d ENGEL, w . (1976) In vitro inhibition of cyclic A M P p h o s p h o d i e s t e r a s e b y cortisol. Nature, 262, 5 9 3 - 5 9 4 SCHWEDES, u . , WEHNER, H . , LEUSCHNER, u . , SCHOFFLING, K. and u s ADEL, K. H . (1974) D e v e l o p m e n t a n d function of isologous transplants of cell suspensions of fetal a d r e n a l glands in t h e r a t . Acta Endocrinologica, Suppl. 184, 59 SEGAL, B . M. a n d CHRISTY, N.
The demand for aldosterone decreases, for example, under chronic excessive ACTH stimulation, as occurs in some animals with implanted pituitary tumors, when the amount of DOC secreted by the zona fasciculata increases sufficiently to satisfy the mineralocorticoid requirement of the animal (Nickerson, Brownie and Molten, 1970; Nickerson, 1975). The glomerulosa may become limited to foci under the capsule, no longer forming a continuous layer (Neville and O'Hare, 1982; Payet and Lehoux, 1982). This indicates that under the combined effect of chronic overstimulation with ACTH and lack of glomerulosa stimulation the critical point in the gradient has moved outward to reach the capsule itself.
Journal of Clinical Endocrinology and Metabolism, 59, 643-651 siMONiAN, M . H . a n d GILL, G. N. (1979) R e g u l a t i o n of deoxyribonucleic acid synthesis in b o v i n e 104, 5 8 8 - 5 9 5 a d r e n o c o r t i c a l cells in c u l t u r e . Endocrinology, siMONiAN, M . H . a n d GILL, G. N. (1981) R e g u l a t i o n of t h e fetal h u m a n a d r e n a l cortex: effects of a d r e n o c o r t i c o t r o p i n o n growth and function of m o n o l a y e r cultures of fetal a n d definitive z o n e cells.