By Errol C Friedberg
With a Foreword by means of Sydney Brenner (Nobel laureate in body structure or medication, 2002)
This biography information the lifetime of Paul Berg (Emeritus Professor at Stanford University), tracing Berg's existence from delivery, in 1926, to the current, with specified emphasis on his huge, immense medical contributions, together with being the 1st to increase expertise that ended in gene cloning technology. In 1980, Berg obtained a Nobel Prize in chemistry for this work.
as well as his contributions within the examine laboratory, Berg orchestrated and oversaw a old assembly at Asilomar, California that founded on a threatening controversy surrounding the conception by way of many of the destructive capability of recombinant DNA know-how. This assembly did a lot to stop this controversy and to install position the legislation of recombinant DNA paintings, therefore placing fears to rest.
The recombinant DNA controversy used to be a old final result of the invention of gene cloning. particularly, it represented a paramount instance of medical foresight and due diligence via the medical group, instead of by way of regulatory entities within the usa and plenty of different nations. the final word reputation of gene/DNA cloning resulted in a brand new period of recent biology that prospers to the present.
This ebook is aimed basically at scientists and people in education. The publication strives to easily offer info for the final reader, yet isn't really particularly adapted for a basic interpreting audience.
whereas many books hide the recombinant DNA controversy, none have satisfactorily addressed this old interval and are frequently contradictory concerning the many who is, where's, and why's concerned. also, the good majority of those have been written via non-scientists. This biography of Paul Berg offers entry to varied archived letters and files at Stanford collage no longer formerly addressed, and to the chronology of occasions as recalled and documented by means of him, in addition to different key personalities, a lot of whom have been interviewed.
Readership: Researchers, graduate scholars, undergraduates in lifestyles sciences, medication and chemistry and lay public.
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Additional info for A Biography of Paul Berg : The Recombinant DNA Controversy Revisited
They spoke chiefly Yiddish (and occasionally Russian) at home. This arcane language was the first that young Paul learned to speak fluently. In fact he didn’t learn to converse in English until he attended kindergarten. “Before attending kindergarten there was nothing unusual about Jewish kids speaking Yiddish, the language that my family was most comfortable with,” Berg related. ”9 In due course, Paul’s parents moved to a four-family row house in the East New York section of Brooklyn. The family was among a minority in the neighborhood without a private telephone, relying instead on a public phone in a nearby candy store for communication.
Indd xxix 23-05-2014 12:04:11 b1674 The Recombinant DNA Controversy Revisited b1674_FM xxx A Biography of Paul Berg left to others. Recombinant DNA technology heralded the feasibility of sequencing the entire human genome, comprising billions of nucleotides. The subsequent sequences of the genomes of multiple other organisms, both unicellular and multicellular, now number in the hundreds. These efforts have greatly enriched molecular and evolutionary genetics. Recombinant DNA technology has also facilitated stunning progress in medicine and pharmacology, as well as genetic engineering in animals and plants, and still offers the promise of gene therapy.
Indd 24 23-05-2014 09:57:48 b1674 The Recombinant DNA Controversy Revisited b1674_Ch-03 College — and World War II 25 school for about three months and were then promptly commissioned as ensigns (formally equivalent to the rank of second lieutenant in the other armed services). The pair parted company when as newly minted officers Rifkin was assigned to duty in the Pacific while Berg was dispatched to the deck officer training facility at Key West, Florida. They would resume their friendship at the war’s end when both returned to Penn State to complete their college education.